Talks and Posters

Dr. Karl-Heinz Ott  ottk@expertbioinformatics.com

  1. Nelly Aranibar, Karl-Heinz Ott, Lindsay Tomlinson, Mark Tirmenstein, Michael Bennett, Joseph Horvath, Greg Cosma, Vasanthi Bhaskaran, Jeff Vassallo, Lloyd Lecureux, Lois Lehman-McKeeman, Identification of Biomarkers for Toxicity by NMR-Based Metabonomics, Small Molecule NMR Conference, Chamonix, CH, 2009
  2. Karl-Heinz Ott, Rui-Ru Ji, Susan Wee, Jian Cao, Petra Ross-MacDonald, Brent Rupnow, Tai Wong PRI Symposium, 2009
  3. Xiadi Zhou, Rolf Ryseck, Karl-Heinz Ott, Christopher Miller, Kelly Covello, Joseph Dinchuk PRI Symposium, 2009
  4. S.L. Posy, S.R. Johnson, K.H. Ott, M. Hermsmeier, W. Vaccaro, PRI Symposium, 2009
  5. F.Myers, J.Wang, K.H.Ott, J.Corradi, M.Cockett, C.Miller, J.Dinchuk , PRI Symposium, 2009
  6. Karl-Heinz Ott, Joseph Dinchuk, John Corradi, Doreen Hewston,
    Diane Cooper, Jian Chen, Siew Ho, Mark Cockett, Chris Miller, Michael Cucolo PRI Symposium, 2008.
  7. J. Whitman, D. Hewston, W-P. Yang, B. Guan, K-H. Ott  PRI Symposium, 2008.
  8. J.E. Dinchuk, C. Cao, F. Huang, K. Reeves, J. Wang, F. Myers, K-H Ott, G. Cantor, M. Gottardis, J. Carboni  PRI Symposium, 2008.
  9. Jian Chen,  Karl-Heinz Ott, Joseph Dinchuk, Doreen Hewston, Diane Cooper, Siew Ho, Christopher Miller  PRI Symposium, 2008
  10. Karl-Heinz Ott, Nelly Aranibar, Petia Shipkova,  Serhiy Hnatyshyn, Mark Sanders, Steven Stryker, Brian Gemzik, Evan Janovitz, Bo Wen, Christine Huang, Wenjun Huang, Aiqing He. Toxin-induced Cholestasis: Integrated Metabonomics and Transcriptomics for Hypothesis Generation and Mechanistic Studies.  Advances in Metabolic Profiling, Boston, 2007
  11. David M. Nelson, Jeffrey D. Vassallo, Nelly Aranibar, Karl-Heinz Ott, Petia A. Shipkova, Lloyd W. Lecureux, Lois D. Lehman-McKeeman PRI Scientific Symposium 2007.
  12. Aranibar, Nelly; Cantone, Joseph; Ford, Michael; Lecureux, Lloyd; Lehman-McKeeman, Lois; Aranibar, Nelly; Nelson, David; Ott, Karl-Heinz; Sanders, Mark; Shipkova,  Petia NMR, GCMS and LCMS metabolic profiling integrated with toxicogenomics analysis in the investigation of endocrine toxicity of the CRF R1 inhibitor DPC 904. Chemical and Pharmaceutical Structure Analysis 2007
  13. Karl-Heinz Ott: Metabolomics as a tool for drug safety studies.  Chemical and Pharmaceutical Structure Analysis 2007
  14. Aranibar, Nelly; Ott, Karl-Heinz; Roongta, Vikram; Shenker, Andrew; Caceres Cortes, Janet, Analytical Method Optimization for Addressing Challenges in Metabolomics Analysis of Clinical Population,  Experimental NMR Conference, Asilomar, CA 2007
  15. Karl-Heinz Ott and Nelly Aranibar Metabolomics in Support of Drug Discovery and Development, Advances in Metabolic Profiling, London, Oct. 2006
  16. Roongta, Vikram; Aranibar, Nelly; Caceres Cortes, Janet; Khandelwal, Purnima; Ott, Karl-Heinz; Qiu, Feng New NMR methods in Pharmaceutical Discovery and Development Eastern Analytical Symposium, Nov 2006
  17. L. Tomlinson, M. Tirmenstein, J. McAlister, N. Aranibar, K.-H. Ott, J. Kozlosky, L. Curtis, G. Cosma, PRI Symposium 2006
  18. Jeffrey D. Vassallo, Nelly Aranibar, Karl-Heinz Ott, Lois Lehman-McKeeman: Metabonomic PRI Symposium 2006
  19. Bethanne M. Warrack, Serhiy Hnatyshyn, Karl-Heinz Ott, Haiying Zhang, Mark Sanders PRI Symposium 2006
  20. Karl-Heinz Ott, Janet Caceres Cortes, Nelly Aranibar, Vikram Roongta, Andrew Schenker  PRI Symposium 2006. (received Award)
  21. Joseph E. Dinchuk, Fanny Myers, Jeanne Wang, Mark Cockett, Janusz Kostanski, Karl-Heinz Ott, Christopher Miller, Siew Ho, Kim McIntyre, Gary Schieven, Marco Gottardis, Ricardo Attar, PRI Symposium 2006
  22. Nelly Aranibar, Karl-Heinz Ott, Lois Lehman-McKeeman, Lindsay Tomlinson, Joseph Horvath, Jeff Vassallo, John Koslosky, Lindsay Curtis, Vikram Roongta, Glenn Cantor, Greg Cosma PRI Symposium 2006
  23. Karl-Heinz Ott and Nelly Aranibar Metabolomics in Support of Drug Discovery and Development, Boeringer Metabolomics Seminar, Bieberach, Germany, Aug. 2006
  24. Warrack, Bethanne; Ott, Karl-Heinz; Sanders, Mark; Hnatyshyn, Serhiy; Shipkova, Petia; Zhang, Haiying: Investigation of a Potential Marker for Phospholipidosis: Normalization Strategies for Metabonomic Analysis of Urine Samples ASMS Conference on Mass Spectrometry, Mai 2006.
  25. Traeger, Sarah; Caceres Cortes, Janet; Darienzo, Celia; Lehman-McKeeman, Lois; Nelson, David; Ott, Karl-Heinz; Roongta, Vikram: Application of High Resolution Magic Angle Spinning NMR for the Study of Biological Tissues. Eastern Analytical Symposium (EAS) , Nov 2005
  26. Nelly Aranibar and Karl-Heinz Ott NMR Methods for Metabolomcis University of Princeton, NJ Nov 2005
  27. Karl-Heinz Ott and Nelly Aranibar “Metabonomics in Drug Discovery and Development” AG-Genomics Symposium, Princeton, New Jersey, Nov. 2005
  28. Haiying Zhang; Bethanne Warrack; Serhiy Hnatyshyn; Nelly Aranibar; Mark Friedrichs;  Karl-Heinz Ott; Kenneth Ray; Mark Sanders. “A Pooled Sample Strategy for the Identification of Potential Biomarkers Utilizing Mass Defect Splitting on High Resolution LC/MS Data” 53nd ASMS Conference, San Antonio, TX, 2005.
  29. Serhiy Hnatyshyn, Bethanne Warrack, Haiying Zhang, Karl-Heinz Ott, Mark Sanders : Extracting Meaningful Information from LC/FTMS Biochemical Profiles in Metabonomics Studies, BMSIARC 2005.
  30. Haiying Zhang; Bethanne Warrack; Serhiy Hnatyshyn; Karl-Heinz Ott; Mark Sanders. “Detection & Validation for Markers of Changes. Utilizing High Resolution LC/MS Data: Methodology & Case Studies” BMSIARC, 2005.
  31. Nelly Aranibar and Karl-Heinz Ott BMS Analytical Research Symposium November 2004 Hopewell, New Jersey
  32. Karl-Heinz Ott and Nelly Aranibar PRI Scientific Symposium 2004 New Brunswick, New Jersey
  33. Sharon Callahan, Jinsong Xing, Janet Caceres-Cortes, Nelly Aranibar, and Karl-Heinz Ott “PRI Scientific Symposium 2004 New Brunswick, New Jersey
  34. M. M. Halleck, C. J. Ziegra, A. E. Schuster, D. M. Garner, N. Aranibar, K. Ott, and K. He.  PRI Scientific Symposium 2004 New Brunswick, New Jersey
  35. Nelly Aranibar, Karl-Heinz Ott, Terry Van Vleet, Glenn Cantor, Ronald Cox, Ron W. Weinzapfel, Martin Smith, Maria Helfrich, Laura Hatfield, Donald Cummings, Vikram Roongta, Adrienne Tymiak, Robert Bruccoleri, Nathan Siemers, Bruce Car, Mark Dominick, Robbie Waites. PRI Scientific Symposium 2004 New Brunswick, New Jersey.
  36. Isaac Neuhaus, Xin Huang, Karl-Heinz Ott, Nelly Aranibar, Charles Tilford, Jansen Lim, Uday Lad, Carlos Rios, John Hinsdale, Robert Bruccoleri and Nathan Siemers  PRI Scientific Symposium 2004 New Brunswick, New Jersey.
  37. Sanders, M., Grubb, M.,  Hnatyshyn,S., Josephs, J., Langish, R., Ott, K-H., Ray, K., Shipkova,P., Warrack, B.  and Zhang, H..  “Application of the LTQ-FT to Metabolite Profiling and Identification” Thermo Electron Users Meeting at the ASMS, in Mannheim, Germany and in Munich, Germany 2004.
  38. Sanders, M., Grubb, M., Hnatyshyn,S., Josephs, J., Langish, R., Ott, K-H., Ray, K., Shipkova,P., Warrack, B.  and Zhang, H..  “Practical Applications of LC/FTMS in Support of Metabolite ID Studies and Metabonomics”, Drug Metabolism Gordon Research Conference, Holderness School, NH 2004
  39. Warrack, B., Hnatyshyn, S., Ott, K-H., Ray, K., Tymiak, A., Zhang, H.,  Sanders, M. Application of LTQ-FTMS to Metabonomic Profiling 52nd ASMS Conference on Mass Spectrometry and Allied Topics: Nashville, TN. 2004
  40. Neuhaus, N., Huang, X., Tilford, C., Ott, K-H., Bruccoleri, R., Siemers, N. “The test of truth-An approach for assessing algorithm and data quality in Affymetrix gene chip studies. ”  Biology of Genomes, Cold Spring Harbor, CT 2004.
  41. N. Araníbar, K-H. Ott, L. Mueller, N. Contel, V. Roongta “Comparison of Various Watersuppression Techniques on Statistical Analysis of 1D Proton NMR Data for Metabonomics” Experimental Nuclear Magenetic Resonance Conference, Savanna, GA. 2003
  42. K-H Ott  “NMR based Metabonomics.” Invited talk at the ACS Meeting of the NMR Topical Group, Woodbridge, NJ, 2003.
  43. K-H Ott  “Metabolic Profiling of Plants by Nuclear Magnetic Resonance and
    Artificial Neural Networks.
    ” Invited talk at “Investigative Gene Function Forum” Cambridge, GB, 2002.
  44. N. Aranibar, B. Singh, G. Stockton, K-H Ott  “Metabolic Profiling in Plants” Poster at the 43rd Experimental NMR Conference, Assilomar, CA,  2002.
  45. I. Neuhaus, X. Huang, D. Jackson,  K-H Ott, N. Siemers  “Expression Profiling at BMS.” Poster at the BMS Scientific Symposium, Wallingford 2001.
  46. Weiss, C., Sturmer, S., Cozzitorto, J., Ott, K., Reinero, A. “Isolation of plant cDNAs encoding secreted and membrane proteins”.  Plant Physiology Meeting, Toulouse, France,  2000.
  47. Ott, K-H., Bass, R., Chiarello, J., Hadcock, J., Rajan, S. “Bio-active Conformations of Somatostatin Agonists and Antagonists” XVIIth International Conference on Magnetic Resonance in Biological Systems, Keystone, USA, 1996.
  48. Ott, K-H., Kwagh, J.G., Stockton, G.W., Kakefuda, G. “Rational Molecular Design of Herbicide Resistant Acetohydroxyacid Synthase” 2nd European Conference of Stable Isotope Aided NMR of Biomolecules, Frankfurt, Germany, 1996.
  49. Ott, K-H., Kwagh, J.G., Stockton, G.W., and Kakefuda, G.  “Rational Molecular Design of Herbicide Resistant Acetohydroxyacid Synthase” Protein Folding and Design, Bethesda, MA, 1996.
  50. Ott, K-H., Kwagh, J.G., Stockton, G.W. and Kakefuda, G.  “Genetic Engineering of Herbicide Resistant Plants by Rational Structure-Based Design of Acetohydroxyacid Synthase”. Tuskegee University, 1996.
  51. Ott, K-H., Kwagh, J.G., Stockton, G.W. and Kakefuda, G.  “Genetic Engineering of Herbicide Resistant Plants by Rational Structure-Based Design of Acetohydroxyacid Synthase” New York Area Plant Molecular Biologists Meeting, New Brunswick, NJ, 1996.
  52. Ott, K-H., Kwagh, J.G., Stockton, G.W. and Kakefuda, G.  “Annual Meeting of the American Society of Plant Physiologists”, San Antonio, TX. 1996.
  53. Ott, K-H., Kakefuda, G., Kwagh, J.G., and Stockton, G.W. “Rational Design of Acetohydroxyacid Synthase Mutants and Herbicide Resistant Crops” Joint Meeting of the British Biophysical Society and the Australian Biophysical Society. Sydney, Australia, 1995.
  54. Ott, K-H., Kwagh, J.G., Stockton, G.W. and Kakefuda, G. “Rational Design of Herbicide Resistant Acetohydroxyacid Synthase” International Live Science Symposium, Boston, 1995.
  55. Ott, K-H., Kwagh, J.G., Stockton, G.W. and Kakefuda, G. “Rational Design of Herbicide Resistant Acetohydroxyacid Synthase” Protein Society First European Symposium, Davos, CH, 1995.
  56. Ott, K-H., Kwagh, J.G., Stockton, G.W. and Kakefuda, G. “Rational Engineering of Herbicide Resistant Acetohydroxyacid Synthase”,  Yale University, 1995.
  57. Ott, K-H., Kwagh, J.G., Stockton, G.W. and Kakefuda, G. “Computer Assisted Design of Herbicide Resistant Acetohydroxyacid Synthase” Rutgers University, 1995
  58. Ott, K-H., Kwagh, J.G., Stockton, G.W. and Kakefuda, G.  “Rational Engineering of Herbicide Resistant Acetohydroxyacid Synthase” Rider University, 1995.
  59. Ott, K-H., and Meyer, B., “Conformational Studies of the N-type Biantennary Decasaccharide” XVI th International Conference on Magnetic Resonance in Biological Systems, Veldhoven, The Netherlands (Abstract C8) 1994.
  60. Ott, K-H. “Protein Modeling”,  International Analytical Conference, 1994, Parsippany, NJ. 1994.
  61. Ott, K-H., G. Kakefuda, S. Rajan, and G. Stockton  “A Three Dimensional Structure of AHAS Determined by Protein Homology Modeling” International Analytical Conference, Parsippany, NJ, (Abstract p 69) 1994.
  62. Ott, K-H., R. Bass, J. Chiarello, J. Hadcock, B. Patel, S. Rajan, and G. Stockton “Conformational Analysis of a Highly Flexible Peptide. Nuclear Magnetic Resonance Spectroscopy and Molecular Dynamics Simulations”.  International Analytical Conference, 1994, Parsippany, NJ, (Abstract p 64) 1994.
  63. Ott, K-H., Rüterjans, H., “NMR Investigation on a 20 Base pair Oligonucleotide”, International Conference on Magnetic Resonance in Biological Systems, Warwick, UK, 1990.
  64. Ott, K-H., and Rüterjans, H., “NMR Investigations on a 20 base pair Oligonucleotide”, Conference on Magnetic Resonance on Biosystems, Schliersee, Germany (Abstract P4) 1989.
  65. Ott, K-H., and Rüterjans, H., “NMR Investigations on a 20 Base Pair Oligonucleotide”,  Joint Meeting of the Austrian, German, Swiss, and Yugoslav Biophysics Societies, Todtmoos, Germany, (Abstract P35), 1989.